GHK-CU

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper peptide complex found in human plasma, saliva, and urine, with plasma concentrations declining significantly with age. As a tripeptide-copper chelate, GHK-Cu has been the subject of extensive research into its multifaceted biological activities, particularly in the domains of skin biology, wound healing, and anti-aging science. Studies have investigated its role in stimulating the production of collagen, elastin, and glycosaminoglycans, the structural proteins and compounds that maintain skin firmness, elasticity, and hydration. Research has also examined its capacity to activate antioxidant defence systems, with findings suggesting it may upregulate the expression of genes involved in cellular repair and protection against oxidative stress. In wound healing research, GHK-Cu has been studied for its ability to accelerate skin recovery, enhance angiogenesis, and modulate inflammatory responses. Additionally, preclinical studies have explored its potential to stimulate hair follicle activity, making it of interest to researchers studying alopecia and scalp health. Its broad regenerative profile positions GHKCu as one of the most comprehensively studied cosmetic and therapeutic peptides in current literature.